First animal cloned from an adult cell

A Finn Dorset sheep called Dolly (named after country singer Dolly Parton) was the first animal to be successfully cloned from an adult cell, as revealed in February 1997 by Dr Ian Wilmut (UK) at the Roslin Institute near Edinburgh, Scotland, UK. This was achieved using a sheep ovum whose DNA-containing nucleus had been removed and replaced with the DNA-containing nucleus of a cell obtained from a 6-year-old Finn Dorset sheep’s udder. The result was a developing embryo that was then transferred to a surrogate Scottish Black Face sheep. Five months later, on 5 July 1996, this ewe gave birth to a healthy female Finn Dorset lamb that was genetically identical to the 6-year-old Finn Dorset from which the original udder cell nucleus had been derived. That lamb was Dolly, who survived to maturity and gave birth to lambs of her own via natural means. She was euthanised on 14 February 2003, aged six and a half, after developing a progressive lung disease.